Category Archives: aromatase inhibitors

The Aromatase Musculoskeletal Syndrome

An article appearing in Arthritis Care and Research looked at the peculiar syndrome of aches and pains found in women who take aromatase inhibitors for breast cancer.arimidex

The authors found that the musculoskeletal symptoms occurred in more than 50 per cent of treated women generally by 8 weeks. Focal areas of inflammation affecting tendons and joints in the hands and feet were the major findings. Later stage cancer and poorer quality of life were predictors of symptom development.

This is actually a fairly common problem I’ve seen.  It can be very debilitating.

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Vitamin D- The antidote for aches and pains from breast cancer treatment?

Kate O’Rourke writing in Pain Medicine News  reported on a study presented at the American Society of Clinical Oncology.  Researchers stated, “High-dose vitamin D is effective at combating joint pain, a common side effect of aromatase pink-ribbon-breast-cancer-awarenesstherapy used to treat breast cancer.

The lead researcher Dr. Qamat Khan at the University of Kansas Medical Center stated, “50% of breast cancer patients taking aromatase inhibitors report musculoskeletal pain.”arimidex

While the exact mechanism remains unknown, ” estrogen deprivation may play a role.”

In addition to pain relief, patients also reported an improvement in fatigue with the vitamin D therapy.vitamin-d-capsules

This news is important since so many patients suffer from this syndrome.

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