Category Archives: Tuberculosis

TB Hides In Bone Marrow

Michelle Fay Cortez writing in Bloomberg News reported on a study in “Science Translational Medicine.  Researchers said they have uncovered the first evidence of tuberculosis hiding in mesenchymal stem cells in the bone marrow of people treated for the disease.”

tb-bacteriaAccording to the article, “the bacteria’s hideout in the self-renewing cells, where they capitalize on protection from the body’s own immune system, may explain how the germs survive.”

This is disturbing news since these sequestered tuberculosis bacteria can be protected from drugs used to eradicate them.

This has important  implications for patients intending to go on biologic therapy for rheumatoid arthritis and other diseases.

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Arthritis anti-TNF users more likely to get lung infections

According to a study published in the Annals of the Rheumatic diseases, patients anti-tnf-drugswith arthritis who take anti-TNF drugs were more than 4 times as likely to develop mycobacterial disease (eg, tuberculosis) and 14 times more likely to die from these diseases than patients not taking the medications.tuberculosis

The study was from the University of Oregon and looked at a database of 8,418 patients who took anti-TNF drugs from 2000 to 2008.

These findings are a bit shocking and surprising but underscore the need for vigilance.

For more information on rheumatoid arthritis treatments and other arthritis problems go to:

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And don’t forget to sign up for  free weekly arthritis tips and a free copy of our special report “The Consumer’s Guide to Arthritis”

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