Know about aspirin resistance?

Many people who take aspirin for prophylaxis against heart attack and stroke have been found to not respond.  Why is that?  Well, the answer is simple.

Elizabeth Mechatie writing in Rheumatology News reported on a study showing that aspirin resistance is actually not resistance at all.  It is due to the enteric coating that many aspirin preparations have.  This phenomenon is called “pseudoresistance.”  When patients who were initially thought to be resistant were switched from enteric coated tablets to plain aspirin, the resistance disappeared.aspirin

One other note: patients who take prophylactic aspirin have the effect of the aspirin blunted if they take non-steroidal anti-inflammatory drugs for conditions such as arthritis.

The exception is Celebrex.

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